XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser

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XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
PRELIMINARY                  PROGRAM

XVI NIBIT MEETING
   Milan, October 11-13, 2018
   San Raffaele Congress Centre, Milan

     Under the auspices of
XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
XV I N I B I T
Scientific Committee
    Alberto Amadori, Padova                                  Massimo Di Nicola, Milano
    Matteo Bellone, Milano                                   Pier Francesco Ferrucci, Milano
    Marco Bregni, Busto Arsizio - VA                         Enrico Proietti, Roma
    Luana Calabrò, Siena                                     Vincenzo Russo, Milano
    Mario Paolo Colombo, Milano

Faculty
    Alberto Amadori                       Massimo Di Nicola                   Federica Moschella
    Università degli Studi di Padova,     IRCCS Istituto Nazionale            Istituto Superiore di Sanità,
    Padova (Italy)                        dei Tumori, Milano (Italy)          Roma (Italy)
    Sebastian Amigorena                   Gianpietro Dotti                    Antonio Moschetta
    Université Paris Descartes,           UNC School of Medicine,             Università degli Studi di Bari
    Paris (France)                        Chapel Hill | NC (USA)              Aldo Moro, Bari (Italy)
    Matteo Bellone                        Soldano Ferrone                     Massimiliano Pagani
    IRCCS Ospedale San Raffaele,          Massachusetts General Hospital,     Università degli Studi di Milano,
    Milano (Italy)                        Boston | MA (USA)                   Milano (Italy)
                                          Pier Francesco Ferrucci             Anna Pastò
    Marco Bregni                          Istituto Europeo di Oncologia
    Azienda Ospedaliera Ospedale                                              Istituto Oncologico Veneto IOV,
                                          IEO, Milano (IT)                    Padova (Italy)
    di Circolo, Busto Arsizio | VA
    (Italy)                               Wolf Herman Fridman                 Giuseppe Procopio
                                          Université Paris Descartes,
    Andrea Botticelli                                                         IRCCS Istituto Nazionale
                                          Paris (France)
    Ospedale Sant’Andrea,                                                     dei Tumori, Milano (Italy)
                                          Vanesa Gregorc
    Roma (Italy)
                                          IRCCS Ospedale San Raffaele,        Enrico Proietti
    Vincenzo Bronte                       Milano (Italy)                      Istituto Superiore di Sanità,
    Università degli Studi di Verona,                                         Roma (Italy)
                                          Niels Halama
    Verona (Italy)                        Universitätsklinikums Heidelberg,   Maria Pia Protti
    Luana Calabrò                         Heidelberg (Germany)                IRCCS Ospedale San Raffaele,
                                                                              Milano (Italy)
    Azienda Ospedaliera                   Alexandre Harari
    Universitaria Senese, Siena (Italy)   CHUV centre hospitalier             Paola Queirolo
    Arianna Calcinotto                    universitaire vaudois,              IRCCS Ospedale San Martino,
    Institute of Oncology Research        Lausanne (Switzerland)              Genova (Italy)
    IOR, Bellinzona (Switzerland)         Guido Kroemer                       Rahul Roychoudhuri
                                          Université Paris Descartes,         Babraham Institute, Cambridge (UK)
    Monica Casucci                        Paris (France)
    IRCCS Ospedale San Raffaele,                                              Marco Ruella
    Milano (Italy)                        Franco Locatelli                    Penn Medicine Hospital of the
                                          IRCCS Ospedale Pediatrico           University of Pennsylvania,
    Mario Paolo Colombo                   Bambin Gesù, Roma (Italy)
    IRCCS Istituto Nazionale                                                  Pennsylvania | PA (USA)
    dei Tumori, Milano (Italy)            Enrico Lugli                        Dario Sangiolo
                                          Istituto Clinico Humanitas,         Università degli Studi di Torino,
    Mark S. Cragg                         Rozzano | MI (Italy)                Torino (Italy)
    University of Southampton,
                                          Chiara Magnani
    Southampton (UK)                      Università degli Studi di Milano
                                                                              Antonio Sica
    Michele De Palma                      Bicocca, Milano (Italy)             Istituto Clinico Humanitas,
    École Polytechnique Fédérale                                              Rozzano | MI (Italy)
                                          Susanna Mandruzzato
    de Lausanne, Lausanne                 Università degli Studi di Padova,   Sjoerd van der Burg
    (Switzerland)                         Padova (Italy)                      Leiden University Medical Centre,
                                                                              Leiden (The Netherlands)
    Anna Maria Di Giacomo                 Massimo Massaia
    Azienda Ospedaliera                   Azienda Ospedaliera Citta’          Laurence Zitvogel
    Universitaria Senese,                 della Salute e della Scienza,       Université Paris-Sud, Paris
    Siena (Italy)                         Torino (Italy)                      (France)

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XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
MEETING
SCIENTIFIC
        THURSDAY - OCTOBER 11
12.30   Light Lunch and registration
14.00   Welcome addresses

        Session 1 - Tumor Microenvironment I
        Chairs: Massimo Di Nicola, Maria Pia Protti
14.15 	Immune and Tumor cell cooperations in shaping
        the tumor microenvironment
        Wolf Herman Fridman (Paris, France)
14.40	In silico modeling of immunotherapy and stroma-targeting therapies
       in human colorectal cancer
        Niels Halama (Heidelberg, Germany)
15.05	Deep interrogation and profiling of tumor-infiltrating T lymphocytes
        Alexandre Harari (Lausanne, Switzerland)
15.30   2 Selected Abstracts

16.00   Coffee Break

        Session 2 - Tumor Microenvironment II
        Chairs: Alberto Amadori, Arianna Calcinotto
16.20 	Myelopoiesis in cancer: “Flipping” over monocytes into immune
        regulatory cells
        Vincenzo Bronte (Verona, Italy)
16.45	Single cell transcriptome analysis of human tumor-infiltrating lymphocytes
        Massimiliano Pagani (Milano, Italy)
17.10   Chemotherapy, innate immunity and tumor metastasis
        Michele De Palma (Lausanne, Switzerland)
17.35   2 Selected Abstracts
18.30   General Assembly of the NIBIT

20.00   Welcome Wine & Cheese

                                                                                    3
XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
XV I N I B I T
SCIENTIFIC PROGRAM
             FRIDAY, OCTOBER 12
             Session 3 - Adoptive Immunotherapy
             Chairs: Marco Bregni, Monica Casucci
    09.00    CAR-T cells in pediatric hematologic malignancies
             Franco Locatelli (Roma, Italy)
    09.25    CAR-T cells in adult hematologic malignancies
             Marco Ruella (Philadelphia, USA)
    09.50    CAR-T cells in adult hematologic malignancies
             Chiara Magnani (Milano, Italy)
    10.15    CAR-T cells in brain tumor
             Gianpietro Dotti (Chapel Hill, USA)
    10.40    1 Selected Abstract

    10.55    Coffee break

             Session 4 - Microbiota and Metabolism
             Chairs: Matteo Bellone, Anna Pastò
    11.15 	The intrinsic role of cholesterol metabolism and nuclear receptors in
            tumorigenesis
             Antonio Moschetta (Bari, Italy)
    11.40    Gut oncomicrobiome fingerprints in cancer
             Laurence Zitvogel (Paris, France)
    12.05 	Metabolic reprogramming and myeloid cell heterogeneity in cancer
             Antonio Sica (Milano, Italy)
    12.30    3 Selected Abstracts

    13.15    Lunch

             Session 5 - Tumor and T cells Interactions
             Chairs: Mario Paolo Colombo, Federica Moschella
    14.15 	Neoantigen landscape dynamics during human melanoma-T cell interactions
             Sjoerd van der Burg (Leiden, The Netherlands)
    14.40 	Understanding agonism: rules and exceptions for TNF receptors
             Mark S Cragg (Southampton, UK)
    15.05 	Tumor-intrinsic PD1 expression: biological role and potential
            therapeutic relevance
             Dario Sangiolo (Torino, Italy)
    15.30    3 Selected Abstracts

4
XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
MEETING
16.00   Coffee break
16.30 	Soldano Ferrone (Boston, USA)
        introduces the Keynote Lecture
        Keynote Lecture: Guido Kroemer (Paris, France)
	Therapeutic manipulation of oncometabolism
        and immunometabolism
20.00   Social Dinner at Terrazza Aperol

        SATURDAY, OCTOBER 13
        Session 6 - Biology of T Cells and Innate Lymphoid Cells in Cancer
        Chairs: Susanna Mandruzzato, Enrico Proietti
09.00 	Control of signal-driven transcriptional programmes in T cells
        Rahul Roychoudhuri (Cambridge, UK)
09.25   Anti-tumor T cell immunity at single cell resolution
        Enrico Lugli (Milano, Italy)
09.50   Epigenetic control of anti-tumor immune responses
        Sebastian Amigorena (Paris, France)
10.15   Vγ9Vδ2 T cells activation by phosphoantigens released by antigen-presenting cells
        Massimo Massaia (Torino, Italy)
10.30   3 Selected Abstracts
11.00   Coffee break

        Session 7 - Clinical and Research Highlights Around NIBIT
        Chairs: Luana Calabrò, Pier Francesco Ferrucci
11.20   Tyrosine Kinase Inhibitors and antitumor immune responses
        Andrea Botticelli (Roma, Italy)
11.40   Immunotherapy in the treatment of urogenital cancer
        Giuseppe Procopio (Milano, Italy)
12.00   Targeted therapies in the treatment of metastatic melanoma
        Paola Queirolo (Genova, Italy)
12.20   Immunotherapy in the treatment of NSCLC
        Vanesa Gregorc (Milano, Italy)
12.40   The NIBIT Foundation Clinical Trials
        Anna Maria Di Giacomo (Siena, Italy)
13.00   NIBIT Awards Nominations
13.30   Lunch
14.30   Adjourn

                                                                                        5
XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
XV I N I B I T
Call for abstract
    All those interested in taking part may submit an abstract in English, following the
    guidelines included in the template.
    The Scientific Committee will analyze all paper and confirm the acceptance to each
    submitter. Papers could be selected as oral presentation or poster presentation.

    DEADLINES FOR ABSTRACT SUBMISSION AND REGISTRATIONS
    	Abstracts should be submitted to the e-mail address alice.trovato@achelois.eu by
       September 17, 2018.
       Abstracts submitted by fax will not be accepted.
    	Abstracts will be reviewed by the Scientific Committee and acceptance will be
       confirmed, together with all details for presenting your work, by September 30,
       2018.
    	The presenting author of an accepted project must register by October 5, 2018.
       Registration is mandatory for presenting the poster.

    COMPETITION AND PRIZE
    Applicants
XVI NIBIT MEETING PRELIMINARY PROGRAM - Milan, October 11-13, 2018 - Professional congress organiser
MEETING
Abstract form
to be sent by e-mail to the Organising Secretariat (alice.trovato@achelois.eu) by
September 17th, 2018.

PRESENTING AUTHOR (Name, Surname, Institution, Institution Address, Department, Mobile phone, e-mail)

OTHER AUTHORS

ABSTRACT TITLE

                      ABSTRACT TEXT (max 2500 characters – including spaces)
Background

Methods

Results

Conclusions

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Signature

                                                                                                                          7
Acknowledgments

Congress Venue
 San Raffaele Congress Centre
 Via Olgettina, 58
 20132 Milan - Italy

Useful Information
 Registration http://achelois.onlinecongress.it/NIBITMeeting2018
 Official website http://www.nibit.org/meeting/index.php

Organising Secretariat
                  Acheloís
                  Professional Congress Organiser
                  Via Olgettina 58 - Milan, IT
                  Phone: +39 02 2643 6227
                  e-mail: linda.isella@achelois.eu
     ACHELOÍS - Professional Congress Organiser
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